Prof. Mehmet Haberal is presented with The Award of The Spanish Order of The Civil Merit (Cruz de Official) by His Majesty King Felipe VI, King of Spain.
We are honored to announce that Prof. Dr. Seza Özen who is the member of Honorary Advisory Board of JBACHS has already won the Aziz Sancar Science Award of TUSEB.
We are happy to announce that The Journal of Basic and Clinical Health Sciences (JBACHS) is indexed by the Emerging Sources Citation Index since November 2017, and indexed by the Ulakbim-TR since 2017.
Journal of Basic and Clinical Health Sciences 2020 , Vol 4 , Issue 2
Are There Any Sex-Depended Differences in Water Transporting Proteins of Choroid Plexus in Mice?
Berna Sözen1,Güneş Aytaç2,Necdet Demir3,Bikem Süzen4,Gamze Tanrıöver3
1California Institute of Technology, Division of Biological Engineering, California, USA
2Yüksek Ihtisas University, Department of Anatomy, Ankara, Turkey
3Akdeniz University, Department of Histology and Embryology, Antalya, Turkey
4Akdeniz University, Department of Anatomy, Antalya, Turkey
DOI : 10.30621/jbachs.2020.1010 Background: It is known that sex hormones show modulatory effects on the central nervous system (CNS). Various CNS pathologies show sex-related differences in terms of rates, symptoms, and the course of the disease. Some of the functions of choroid plexus (CP) are under the control of sex hormones. The aim of this descriptive study was to evaluate sex effects on CP water channels.

Methods: Expressions of Aquaporin (AQP) 1, 2 and 4 proteins in CP were compared between in male and female Balb/C mice brains; and also in different stages of the estrous cycle, with immunohistochemistry.

Results: No difference is observed for AQP 1, 2 and 4 immunoreactivities in male and female brain, including different stages of the estrous cycle.

Conclusion: In conclusion, to the best of our knowledge, AQP2 expression was shown in the CP for the first time, and no sex hormonedependent differences were found in terms of expressions of AQP1, 2 and 4. Keywords : choroid plexus, water channels, sex differences, aquaporin 1, aquaporin 2, aquaporin 4