Prof. Mehmet Haberal is presented with The Award of The Spanish Order of The Civil Merit (Cruz de Official) by His Majesty King Felipe VI, King of Spain.
We are honored to announce that Prof. Dr. Seza Özen who is the member of Honorary Advisory Board of JBACHS has already won the Aziz Sancar Science Award of TUSEB.
We are happy to announce that The Journal of Basic and Clinical Health Sciences (JBACHS) is indexed by the Emerging Sources Citation Index since November 2017, and indexed by the Ulakbim-TR since 2017.
Journal of Basic and Clinical Health Sciences 2020 , Vol 4 , Issue 3
A Review on The Development, Production Strategies, and Utilization of Monoclonal Antibodies
Gamze Sanlav1,Omer Bekcioglu1,Yasemin Basbinar2
1Dokuz Eylul University, Department of Oncology, İzmir, Turkey
2Dokuz Eylul University, Department of Translational Oncology, İzmir, Turkey
DOI : 10.30621/jbachs.2020.1243 Over the last 20 years, monoclonal antibodies have become the backbone of biological therapeutics for the treatment and diagnosis of several diseases. The rising incidence of cancer and other immunologic diseases promoted the increasing investments of the global pharmaceutical industry in monoclonal antibody development. The R&D has focused on the highest efficacy which is majorly correlated with the antigenbinding specificity and the lowest immunogenicity of monoclonal antibodies. This review aims to provide a brief description and explanation of each stage in the development path of mAbs. Keywords : monoclonal antibodies, industry, cancer